The STEM Brain Cell Lab studies the cellular and molecular mechanisms of brain injury and neural circuit repair using human stem cell–based systems. Our research integrates stem cell biology, brain organoids, CRISPR functional genomics, and neuroengineering to model neurological disease and develop strategies for neural regeneration.
We develop engineered neural stem cell platforms designed to enhance neuronal connectivity and functional integration after brain injury. Our work combines stem cell biology, gene engineering, and circuit neuroscience to advance regenerative strategies for the central nervous system
We build human stem cell–derived cortical organoids to model brain injury and neurological disease. These systems allow us to study cellular responses, circuit disruption, and mechanisms of repair in a controlled human model.
Our laboratory investigates the cellular and molecular mechanisms of traumatic brain injury, including concussion and circuit-level damage. Using both in vivo models and human stem cell systems, we aim to identify pathways that support neural repair and recovery.
We study how neurons establish and rebuild long-range connections in the injured brain. By decoding the molecular programs that guide axon growth and synaptic integration, we aim to develop strategies for rebuilding functional neural circuits
